Enzymes in the soil are closely related to the physical, chemical and biological characteristics of the soil and regulate the formation of soil fertility, organic matter, nutrient mineralization and cycling in nature. As soil contains several enzymes the objective of the conducted experiment was to estimate dehydrogenase, acid phosphatase, glucosidase, protease, catalase and amylase in five coconut based cropping systems viz.,
Coconut+Fodder, Coconut+Banana, Coconut+Pepper, Coconut+Tuber and Coconut+Vegetable under organic and conventional farming systems and find out the biologically fertile cropping system using enzyme activity number (EAN) and enzyme kinetics for good cropping system in mid-laterite soils of Kollam district of Kerala AEU 9. The dehydrogenase, acid phosphatase and catalase activity were found to be higher in Coconut + Banana under organic farming system, glucosidase and amylase activity was more in Coconut + Pepper under organic farming system and protease activity was found to be higher in Coconut + Tuber cropping system under organic management system. Coconut + Banana under organic farming situation was found to be best cropping system compare to other cropping systems.