Vol. 7, Issue 11, Part A (2025)

This study sought to evaluate the effects of yogurt fortified with concentrated green tea extract and the drug orlistat on the health characteristics of obese experimental mice. The outcomes of administering a high-fat diet (T₂), a standard diet (T₁), and a high-fat diet supplemented daily with 2 cc of yogurt (T₃). The effects of a high-fat diet augmented with daily administrations of concentrated green tea extract (T₄) and orlistat (T₅) on several physiological parameters were evaluated, including body weight, total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and liver enzymes in serum of male obese rats. The therapies were administered orally via gavage. The adult rats were weighed and randomly assigned to five groups. The primary findings indicate that obesity led to a marked decrease (p≤0.05) in HDL-C levels and a significant increase (p≤0.05) in animal body weight, as well as in cholesterol, triglycerides, and LDL-C concentrations, relative to the control group. The findings indicate that the groups consuming yogurt fortified with green tea extract had markedly elevated HDL levels and considerably reduced (p≤0.05) body weight, cholesterol, triglycerides, LDL-C, AST, ALT, and triglycerides.