Vol. 7, Issue 4, Part C (2025)

Red dragon fruit (Hylocereus polyrhizus) is gaining attention as a nutrient-rich tropical fruit with high antioxidant potential and bioactive compounds such as betacyanins, flavonoids, and polyphenols, offering numerous health benefits including anticancer, antidiabetic, and cardioprotective effects. As global consumption of nutrient-poor soft drinks rises, this review highlights the nutritional importance of incorporating red dragon fruit into the diet to enhance overall health. Research reveals that its bioactive profile varies across developmental stages and parts of the fruit, with the peel often containing higher concentrations of phenolic compounds and flavonoids. Betacyanins demonstrate superior antioxidant activity and pH stability compared to other pigments. Studies report its efficacy in lowering blood glucose and cholesterol levels, improving endothelial function, and protecting pancreatic cells, thus contributing to diabetes and cardiovascular disease management. Furthermore, its application in functional foods, such as fermented milk and cookies, has shown positive impacts on taste, nutritional value, and the inhibition of harmful compounds. The findings suggest that red dragon fruit and its by-products can serve as cost-effective, natural alternatives for improving dietary quality and preventing lifestyle diseases. With expanding cultivation and increasing scientific validation, red dragon fruit emerges as a valuable functional food for future health-oriented nutrition strategies.